Monica Baciu

Laboratoire de Psychologie et Neurocognition
CNRS UMR 5105
Université Pierre Mendès-France
Bâtiment Sciences de l'Homme et Mathématiques
BP47, 38040 Grenoble Cedex 9 France

I am a Professor of Cognitive Neuroscience in the department of psychology of Pierre Mendès-France University, Grenoble. Currently, I am the head of the Laboratory of Psychology and Neurocognition, CNRS UMR 5105. I am a neurologist and also did training in the field of neuroscience research. From 1990-1995 I was a resident and then a staff neurologist at Cluj Hospital in Romania. I relocated to Grenoble, France in 1995, at which time I entered a degree program in neuroscience research. In 1999 I obtained a PhD in neuroscience from Joseph Fourier University in Grenoble. Since 1999 I have been working as an Assistant, then Associate Professor in Cognitive Neurosciences in the Department of Psychology (UPMF, Grenoble). From 2002-2007 I worked as a research associate for two years at Washington University in St Louis, USA.

• 2002: Qualification to manage research projects – Human Sciences and Psychology, Université Pierre Mendès-France, Grenoble
• 1999: PhD in Neuroscience, Université Joseph Fourier, Grenoble
• 1996: MS Neuroscience, Université Joseph Fourier, Grenoble
• 1994: Specialist in Neurology, Medical School, Cluj, Romania
• 1990: Medical Degree, MD, Medical School, Cluj, Romania

• 2004-present: Professor of Cognitive Neuroscience, CNU 16, Université Pierre Mendès-France, LPNC, Grenoble
• 2006-2008; 2009-2010 : CNRS Research Associate
• July-December 2002; September-December 2003; March-April 2007 - Research Associate - Washington University, Neuropsychology Laboratory St. Louis, USA (Dr Brad Schlaggar, Pr Steve Petersen, Dr Jeff Ojemann)
• 2000-2004: Lecturer in Neuroscience, Université Pierre Mendès-France, LPNC, Grenoble
• 2001-2004: Part-time Research Associate, MRI Unit, Grenoble Hospital (Pr JF Le Bas)
• 1999-2000: Temporary research and teaching associate - Université Pierre Mendès-France, LPNC, Grenoble 
• 1996-1999: PhD student in Neuroscience, Université Joseph Fourier, Laboratoire INSERM U438 “RMN Bioclinique”, Grenoble
• 1995-1996: MS student in Neuroscience, Université Joseph Fourier, Laboratoire INSERM U438 “RMN Bioclinique”, Grenoble
• 1994-1995: Staff neurologist, Cluj Neurology Hospital (Romania)
• 1992-1995: Neurology instructor, Cluj University medical school (Romania)
• 1991-1995: Neurology intern, Cluj Neurology Hospital (Romania)
• 1990-1991: Intern, University Hospital, Cluj, Romania
• 1990-1991: Instructor in Physiology Cluj University, Medical School

My research activity explores the hemispheric specialization and cerebral correlates of language and memory operations, according to several intrinsic and extrinsic variables. This question is addressed in healthy subjects and patients by using behavior and neuroimaging methods (fMRI).

RESEARCH TOPICS

• Hemispheric lateralization for language and memory in healthy subjects and patients
• Cerebral reorganization (plasticity) for language and memory in epilepsy
• Cartography of language and memory during Ageing

METHODS

• Behavioural (divided visual field) experiments
• Neuroimaging

KEYWORDS

• Language, Memory, fMRI, Ageing, Hemisphere specialization, Brain, Epilepsy, Healthy

AWARD

• 2008 Editors' Choice Award from the Organization for Human Brain Mapping : “Relationship between task-related gamma oscillations and BOLD signal: New insights from combined fMRI and intracranial EEG. Human Brain Mapping 28:1368-1375 (2007), Jean-Philippe Lachaux, Pierre Fonlupt, Philippe Kahane, Lorella Minotti, Dominique Hoffmann, Olivier Bertrand, Monica Baciu.

TEACHING

• Functional neuroanatomy
• Cognitive Neuropsychology
• Neurology
• Neuroimaging methods

CURRENT PhD ADVISORY ACTIVITY

• Pauline FAVRE, Cognitive Psychology PhD student, Université Pierre Mendès-France, LPNC Grenoble: Bipolar disorder and Psychoeducation. Behavioral and fMRI study, MENRT fellowship (advisory 100%) 2011-2014.
• Gonthier CORENTIN, Cognitive Psychology PhD student, Université Pierre Mendès-France, LPNC Grenoble:Working memory - behavioural and neuroimaging; MENRT fellowship (advisory 50 %) 2011-2014.
• Benoit FRADCOURT, Cognitive Psychology PhD student, Université Pierre Mendès-France, LPNC Grenoble: Emotion and schizophrenia", MENRT fellowship (advisory 50 %) 2010-2013.
• Yanica KLEIN KOERKAMP, Cognitive Psychology PhD student, Université de Savoie, LPNC Chambéry: " Emotion and aging ", fellowship from Région Rhône Alpes, Cluster 11 (advisory 50 %) 2009-2012.

PREVIOUS PhD ADVISORY ACTIVITY

• Alexandra JUPHARD, PhD Cognitive Psychology, Université de Savoie (2004)
• Emilie COUSIN, PhD Cognitive Psychology, Université Pierre Mendès-France (2008)
• Solène KALENINE, PhD Cognitive Psychology, Université Pierre Mendès-France (2008)
• Marcela PERRONE-BERTOLOTTI, PhD Cognitive Psychology, Université Pierre Mendès-France (2011)
• Gaetan YVERT, PhD Cognitive Psychology, Université Pierre Mendès-France (2012)

OTHER ADVISORY ACTIVITY

• Becky Coalson - Washington University, Saint Louis, USA, Visiting Professor at Pierre Mendès-France University, 2008.
• Adina Mincic - Medical School Oradea, Cluj, Romania, Research Associate at Pierre Mendès-France University, 2012.
• Pénélope Martinelli - ATER Neuroscience, 2012-2013.

• > 2013 Head of LPNC
• 2009-2013: Head of the Research Federative Structure "Health and Society", UPMF, Grenoble
• 2007-2013: leader of the “Language and Memory” research team, LPNC
• 2007-2012: Coordinator of the PhD training program “Engineering for Health, Cognition and Environment” (EDISCE), Grenoble
• 2009-2013: Head of the “Functional neuroimagery Group”, LPNC
• > 2012: Member of Scientific Committee of Pierre Mendès-France University
• > 2012: Member of AERES committees

ARTICLES (SUBMITTED, IN REVISION)

• Favre, P., Baciu, M., Pichat, C., Bougerol, T., Polosan, M. (submitted). FMRI Evidence for Abnormal Resting-State Functional Connectivity in Euthymic Bipolar Patients. American Journal of Psychiatry.
• Klein-Koerkamp, Y., Heckemann, R.A., Moreaud, O., Keignart, S., Krainik, A., Hammers, A., Baciu, M., Hot, P. for the Alzheimer's Disease Neuroimaging Initiative. (submitted). Amygdalar atrophy in Alzheimer's disease: Correlation with cognitive scores. Neuropsychologia.
• Gomez, A., Cerles, M., Rousset, S., Le Bas, JF. & Baciu, M. (in revision). Contextual spatial learning and subsequent re-experiencing cerebral state in temporo-parietal regions. Frontiers Cognition.
• Fradcourt, B., Peyrin, C., Baciu, M., Campagne, A. (in revision). Behavioral assessment of emotional and motivational appraisal during visual processing of emotional scenes depending on spatial frequencies. Brain Cognition.
• Favre, P., Baciu, M., Pichat, C., de Pourtalès, M.A., Fredembach, B., Garçon, S., Bougerol, T. & Polosan, M. (in revision). Modulation of fronto-limbic activity by the psychoeducation in euthymic bipolar patients. A functional MRI study. Psychiatry Research.
• Perrone-Bertolotti, M., Lemonnier, Baciu, M. (in revision). Behavioral evidence for the inter-hemispheric cooperation during a lexical decision task. A divided visual field experiment. Frontiers Neuroscience.

PUBLISHED ARTICLES

• Hot, P., Klein-Koerkamp, Y., Borg C., Richard-Mornas, A., Zsoldos, I., Thomas Antérion, C. & Baciu, M. (2013). Fear recognition impairment in early-stage Alzheimer's disease: When focusing on the eyes region improves performance. Brain Cogn 9;82(1):25-34.
• Grabski, K., Schwartz, JL, Lamalle, L., Coriandre, V., Nathalie, V., Baciu, M., Le Bas , JF., Sato, M. (2013). Shared and distinct neural correlates of vowel perception and production. Journal of Neurolinguistics, 26: 384-408.
• Perrone-Bertolotti, M., Lemonnier, S., Bonniot, C. & Baciu, M. (2013). Hemisphere specialization and inter-hemispheric cooperation during a phonological task. Effect of Lexicality as assessed by the Divided Visual Field approach. Laterality, vol.18:2, 216-230.
• Vanhoucke, E., Cousin, E., Baciu, M. (2013). Effet du vieillissement sur la spécialisation hémisphérique du langage. Méta-analyse des études utilisant le test d'écoute dichotique. Gériatrie et Psychologie NeuroPsychiatrie du vieillissement 2013 ; 11 (1) : 57-64.
• Klein-Koerkamp, K., Baciu, M., Hot, P. (2012). Preserved and impaired emotional memory in Alzheimer's disease. Front. Psychology, 3:331 doi: 10.3389/fpsyg.2012.00331.
• Klein-Koerkamp, Y., Beaudoin, M., Baciu, M., Hot, P. (2012). Emotional Decoding Abilities in Alzheimer's Disease. A Meta-Analysis. J Alzheimers Dis. 32:1, 109-125.
• Perrone-Bertolotti, M., Dohen, M., Loevenbruck, H., Sato, M., Pichat, C., Baciu, M. (2012). Neural correlates of the perception of prosodic focus in French. An fMRI study. Human Brain Mapping, doi: 10.1002/hbm.22090.
• Yvert, G., Perrone-Bertolotti, M., Baciu, M., David, O. (2012). Dynamic causal modeling of spatiotemporal integration of phonological and semantic processes: An electroencephalographic study. The Journal of Neuroscience, 32(12):4297-4306.
• Jacquier C., Bonthoux, F., Baciu, M., Ruffieux, B. (2012). Improving the effectiveness of nutritional information policies: assessment of unconscious pleasure mechanisms involved in food-choice decisions. Nutrition Review, 70(2):118-131.
• Peyrin, C., Démonet, JF., Pernet, C., Baciu, M., LeBas, JF., Valdois, S. (2012). Neural dissociation of phonological and visual attention span disorders in developmental dyslexia: FMRI evidence from two case reports. Brain and Language, 120(3):381-94.
• Perrone-Bertolotti, M., Zoubrinetzky , R., Yvert, G., Le Bas, JF., Baciu, M. (2011). Functional MRI and Neuropsychological evidence for language plasticity, before and after surgery in a patient with left temporal lobe epilepsy. Epilepsy Behav, 23(1):81-6.
• Perrone-Bertolotti, M., Yvert, G. & Baciu, M. (2011). Evaluation de la réorganisation cérébrale du langage chez les patients épileptiques. Apport de la psychologie cognitive. Les Cahiers d'Epilepsies, novembre 2011, p. 9-14.
• Juphard, A., Vidal, J.R, Perrone-Bertolotti, M., Minotti, L., Kahane, P., Lachaux, JP. & Baciu, M. (2011). Direct evidence for two different neural mechanisms for reading familiar and unfamiliar words: an intra-cerebral EEG study. Front Hum Neurosci., 2011;5:101.
• Polosan, M., Baciu, M., Cousin, E., Perrone, M., Pichat, C., Segebarth, C. & Bougerol, T. (2011). Cerebral correlates of social competition behaviour in healthy subjects: An fMRI study. Brain and Cognition Vol.77, Issue 3 Pages 401-411.
• Grabski, K., Lamalle, L., Vilain, C., Schwartz, JL., Vallée, N., Troprès, I., Baciu, M., Le Bas, JF., Sato, M. (2011). Basic neural network and motor somatotopy of supralaryngeal and laryngeal articulators. Human Brain Mapping, epub.
• Perrone-Bertolotti, Pichat, C., Baciu, A., Le Bas, JF, Baciu, M. (2011). Functional MRI evidence for modulation of the cerebral activity by grapheme-to phoneme regularity and gender in French, Journal of Neurolinguistics, Volume 24, Issue 4, July 2011, Pages 507-520.
• Perrone, M., Cousin, E., Baciu, A., Baciu, M. (2009). Modulation de la spécialisation hémisphérique du langage par le degré de transparence grapho-phonémique et le sexe. Etude comportementale en champ visuel divisé. Revue de Neurosychologie, Volume 1, Numéro 4, 288-98.
• Gomez, A., Rousset, S., Baciu, M. (2009). Egocentric-Updating During Navigation Facilitates Episodic Memory Retrieval, Acta Psychologica 132(3):221-7.
• Kalénine, S., Peyrin, C., Pichat, C., Segebarth, C., Bonthoux, F., Baciu, M. (2009). The sensory-motor specificity of taxonomic and thematic conceptual relations: A behavioral and fMRI study. Neuroimage, 44(3):1152-62.
• Cousin, E., Perrone, M., Baciu, M. (2009). Hemispheric specialization for phoneme detection according to phoneme transparency and gender. A divided visual field experiment in healthy subjects. Brain & Cognition69(3):465-71.
• Cousin, E., Baciu, M., Pichat, C., Kahane, P. (2008) Functional MRI evidence for language plasticity in adult epileptic patients. Preliminary results. Neuropsychiatric Disease and Treatment, 4(1), 235-246.
• Lachaux, J.P., Jung, J., Mainy, N., Dreher, J.C., Bertrand, O., Baciu, M., Minotti, L., Hoffmann, D., Kahane, P. (2008). Silence is golden: transient neural deactivation in the Prefrontal Cortex during attentive reading.Cerebral Cortex, 18(2):443-50.
• Mainy, N., Jung, J., Baciu, M., Kahane, P., Schoendorff, B., Minotti, L., Hoffmann, D., Bertrand, O., Lachaux, JP. (2007). Cortical dynamics of word recognition. Human Brain Mapping, 29(11):1215-30.
• Cousin, E., Peyrin, C., Pichat, C., Lamalle, L., Le Bas, J.F., Baciu, M. (2007). Functional MRI method for mapping phonology and semantics in healthy subjects. European Journal of Radiology, 63(2):274-85.
• Lachaux, JP., Fonlupt, P., Kahane, P., Minotti, L., Hoffmann, D., Bertrand, O., Baciu, M. (2007). Relationship between task-related Gamma oscillations and BOLD signal: new insights from combined fMRI and intracranial EEG. Human Brain Mapping, 28(12):1368-75.
• Krainik, A., Rubin, C., Grand, S., David, O., Baciu, M., Jaillard, A., Tropres, I., Lamalle, L., Duffau, H., Le Bas, J., Segebarth, C., Lehericy, S. (2006). Functional magnetic resonance imaging in clinical practice. J Radiol, 87(6): 607-617.
• Cousin, E., Peyrin, C., Baciu, M. (2006). Hemispheric predominance assessment of phonology and semantics. A divided visual field experiment. Brain and Cognition 61, 298-304.
• Valdois, S., Carbonnel, S., Juphard, A., Baciu, M., Ans, B., Peyrin, C. & Segebarth, C. (2006). Polysyllabic pseudo-word processing in reading and lexical decision: Converging evidence from behavioural data, simulations and functional MRI. Brain Research1085(1):149-62.
• Baciu, M.V., Watson, J.M., Maccotta, L., McDermott, K.B., Buckner, R.L., Gillian, F.G., & Ojemann, J.G. (2005). Evaluating fMRI procedures for assessing hemispheric language dominance in neurosurgical patients. Neuroradiology, 47: 835-844.
• Baciu, M., Juphard, A., Cousin, E., & Le Bas, J. F. (2005). Evaluating fMRI methods for assessing hemispheric language dominance in healthy subjects. European Journal of Radiology, 55(2), 209-218.
• Loevenbruck, H., Baciu, M., Segebarth, C., & Abry, C. (2005). Broca's region under focus: An fMRI study of the production of deixis via syntactic extraction and prosodic focus. Journal of Neurolingustics,18 (3), 237-258.
• Peyrin, C., Baciu, M., Segebarth, C., Marendaz, C. (2004). Cerebral regions and Hemispheric Specialization for Processing Spatial Frequencies during Natural Scene Recognition. An Event-Related fMRI study.Neuroimage, Vol. 23, pp 698-707.
• Sato, M., Baciu, M., Loevenbruck, H., Schwartz, J.L., Cathiard, M.A., Segebarth, C., Abry, C. (2004). Multistable Representation of Speech Forms: A Functional MRI Study of Verbal Transformations.Neuroimage, 23(3), pp.1143-1151.
• Baciu, M., Watson, J.M., McDermott, K.B., Wetzel, R.D., Attarian, H., Moran, C.J., & Ojemann, J.G. (2003). Functional MRI reveals inter-hemispheric dissociation of frontal and temporal regions correlated with lexical processing in a patient with frontal lobe epilepsy. Epilepsy & Behaviour, Vol 4 (6), pp 776-780.
• Baciu, M., Le Bas, J., Segebarth, C. and Benabid, A. L. (2003). Presurgical fMRI evaluation of cerebral reorganization and motor deficit in patients with tumorsand vascular malformations. European Journal of Radiology, vol. 46, 139-146.
• Baciu, M., Ans, C., Carbonnel, S., Valdois, S., Juphard, A., Pachot-Clouard,M., & Segebarth, C. (2002). Length effect during word and pseudo-word reading. An event-related fMRI study. Neuroscience Research Communications, 30,155-165.
• Badin, P., Bailly, G., Revéret, L., Baciu, M., Segebarth, C. and Savariaux, C. (2002). Three-dimensional linear articulatory modeling of tongue, lips and face, based on MRI and video images. Journal of Phonetics,30, 533-553.
• Bonaz, B., Baciu, M., Papillon, E., Bost, R., Gueddah, N., Le Bas, J., Fournet, J. and Segebarth, C. (2002). Central processing of rectal pain in patients with irritable bowel syndrome: A fMRI study. American Journal of Gastroenterology, 97(3), 604-661.
• Baciu, M., Kahane, P., Minotti, L., Charnallet, A., David, D., Le Bas, J. and Segebarth, C. (2001). FMRI assessment of hemispheric dominance for language in epileptic patients by using a phonological task.Epileptic Disorders, 3(3), 117-124.
• Baciu, M., Koenig, O., Vernier, M.-P., Bedoin, N., Rubin, C. and Segebarth, C. (1999). Categorical andcoordinate spatial relations. fMRI evidence for hemispheric specialization. NeuroReport, 10, 1373-78.
• Baciu, M., Rubin, C., Décorps, M. and Segebarth, C. (1999). Hemispheric language dominance testing by means of fMRI. Journal of Neuroimaging, 9, 246-247.
• Baciu, M. V., Bonaz, B. L., Papillon, E., Bost, R. A., Le Bas, J.-F., Fournet, J. and Segebarth, C. M. (1999). Central processing of rectal pain: An fMRI study. American Journal of NeuroRadiology, 20, 1290-1924.
• Baciu, M., Rubin, C., Décorps, M. and Segebarth, C. (1999). fMRI assessment of hemispheric language dominance testing using a simple inner speech paradigm. NMR in Biomedicine, 12, 293-298.
• Roth, M., Decety, J., Raybaudi-Baciu, M., Massarelli, R., Delon-Martin, C., Segebarth, C., Morand, S., Gemignani, A., Décorps, M., Jeannerod, M. (1996). Possible involvement of primary motor cortex in mentally simulated movement: A functional magnetic resonance imaging study, NeuroReport, 7, 1280-1284.

BOOKS AND CHAPTERS

• Baciu, M. (2012). Plasticité cérébrale du langage et facteurs de réorganisation en "Variations, évolutions, métamorphoses". Les Colloques de l'Institut Universitaire de France (IUF), pp. 67-91.
• Baciu, M. (2011). Introduction à la Neuroanatomie Fonctionnelle, De Boeck Université. Louvain la Neuve, Belgique.
• Baciu, M., Cousin, E. (2008). Functional MRI assessment of language plasticity in epileptic patients. In “Some aspects of speech and the brain”, Ed. Peter Lang Verlag.
• Baciu, M., Valdois, S., Kandel, S., Spinelli, E., Cousin, E., Peyrin, C., Lallier, M., Juphard, A., Perrone, M., Soller, O., Alvarez, V., Vallée, N. (2008). Neuropsychology and Cognition of language: Behavioural, neuropsychological and neuroimaging studies of spoken and written language, Ed. Research Signpost.
• Juphard, A., Valdois, S., Carbonnel, S., Pichat, C., Ans, B. & Baciu, M. (2008). Length effects in reading: Evidence from behavioural and neuroimaging data. In M. Baciu (Ed.). Neuropsychology and Cognition of Language : Behavioural, Neuropsychological and neuroimaging studies of oral and written language (pp.3-21). Research SignPost.
• Savariaux, C., Vilain, C., Baciu, M., Abry, C., Perrier, P., Lebeau, J., Segebarth, C. (2008). Réorganisation du conduit vocal et réorganisation corticale de la parole: de la perturbation aux lèvres à la glossectomie. R. Jouvent & G. Capouthier "Etudes acoustiques et IRMf. La Cognition réparée?  Perturbations et récupérations des fonctions cognitives". Editions de la Maison des sciences de l'homme.
•  Valdois, S., Peyrin, C & Baciu, M. (2008). The neurobiological correlates of developmental dyslexia. In S. Fuchs, (Eds). Some aspects of speech and the brain. Peter Lang Verlag publisher.
• Savariaux, C., Vilain, C., Baciu, M., Abry, C., Perrier, P., Lebeau J., Segebarth, C. (2007). Réorganisation du conduit vocal et réorganisation corticale de la parole : de la perturbation aux lèvres à la glossectomie. Etudes acoustique et IRMf. In C. Fuchs (ed) "Perturbations et récupérations des fonctions cognitives". Paris, Hermès.
• Vilain C., Baciu M., Savariaux C., Lebeau J., Segebarth C., Abry C., Perrier P. (2007). Stratégies de réorganisation cognitive pour la production de parole d'un patient ayant été opéré d'une glossectomie suivie d'une reconstruction linguale : une étude d'IRM fonctionnelle. In Vaxelaire, B., Sock, R., Kleber, G. & Marsac, F. (eds), Perturbations et réajustements, langue et langage. Publication de l'université M. Bloch, Strasbourg 2, pp. 201-209.
• Baciu, M. (2006). Explorarea substratului cerebral subiacent limbajului utilizînd tehnica de Imagistica Functionala prin Rezonanta Magnetica Nucleara. Ed. Iuliu Hatieganu, Facultatea de Medicina si Farmacie, Cluj-Napoca, Roumanie.
• Baciu, M., Juphard, A., Valdois, S., Carbonnel, S. & Ans, B. (2006). FMRI evidence for ACV98 connectionist model for reading mono- and multi-syllabic words and pseudo-words. In “Brain mapping and language”, New York: NOVA science publishers.